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Monday 26th January 2009
Arrival at Ivalo Airport (Finland). Transfer by bus to Saariselka.
19:00 Welcome words (Outi Hovatta, Peter Andrews, Sebastien Duprat)
Evening: Half board dinner in the hotel restaurant
Possibility to enjoy the hotel saunas.
Tuesday 27th January 2009
Morning breakfast
8:00 – 12:00 Session 1: Culture secrets for hES cells.
8:00-8:10 Session introduction – Outi Hovatta (Karolinska Institute, Stockholm, Sweden)
8:10-9:00 Maintenance of pluripotency – Martin Pera (University of Southern California – Los Angeles, USA)
9:00-9:50 Origin of hESC – Jennifer Nichols (University of Cambridge, UK)
9:50-10:20 Coffee break
10:20-11:10 Lessons from mouse ES cells – Jennifer Nichols (University of Cambridge, UK)
11:10-12:00 Derivation and culture – Outi Hovatta (Karolinska Institute, Stockholm, Sweden)
12:00 – 15:00 Lunch at the hotel
Outdoor activity: Team building in the snow.
15:00 – 19:00 Session 2: Prospects of biomedical applications - I.
15:00-15:10 Session introduction – Timo Otonkoski (University of Helsinki, Finland)
15:10-16:00 Endodermal differentiation – Timo Otonkoski (University of Helsinki, Finland)
16:00-16:50 Pathological modelling of monogenic diseases using hES cells – Marc Peschanski (I-STEM – Evry, France)
16:50-17:20 Coffee break
17:20-18:10 hES cells Hematopoiesis – Elaine Dzierzak (Erasmus University MC, Rotterdam - Netherlands)
18:10-19:00 Technologies for the scaled production of human stem cells – Tim Allsopp (SCS Ltd - Cambridge, UK)
Evening: Half board dinner in the hotel restaurant
Possibility to enjoy the hotel saunas.
Guided walk outside to see the northern lights (21:00-22:00)
(Either on the 27th, 28th or the 29th depending on the weather forecast)
Wednesday 28th January 2009
Morning breakfast
8:00 – 12:00 Session 3: Understanding and manipulating the pluripotency
8:00-8:10 Session introduction – Austin Smith (University of Cambridge, UK)
8:10-9:00 iPS cells – Austin Smith (University of Cambridge, UK)
9:00-9:50 Human ES cells for disease models – Nissim Benvenisty (Hebrew University of Jerusalem, Israel)
9:50-10:20 Coffee break
10:20-11:10 Molecular mechanism of nuclear reprogramming and analysis of the iPS cell state – Kathryn Plath (UCLA school of medicine, Los Angeles, USA)
11:10-12:00 Genetic manipulations – Konstantinos Anastassiadis (University of Dresden, Germany)
12:00 – 15:00 Lunch at the hotel
Outdoor activity OPTION 1: short safari with snow-mobile
Outdoor activity OPTION 2: Snowshoes or cross-country ski
(with guide/teacher for beginners)
15:00 – 19:00 Session 4: Ethics
15:00-15:10 Session introduction – Goran Hermeren (University of Lund, Sweden)
15:10-16:00 hESC-specific ethical issues – Goran Hermeren (University of Lund, Sweden)
16:00-16:50 The reprogramming of cells and rights: ethical and political challenges of the new developmental biology – Giuseppe Testa (University of Milan, Italy)
16:50-17:20 Coffee break
17:20-18:10 Diversity of religious approaches – Kristina Hug (University of Lund, Sweden)
18:10-19:00 Animal trials preceding clinical studies – Kate Millar (University of Nottingham, UK)
Evening: Gala dinner in the Sami Hut (bus transportation)
(with supplement: possibility of a tour with raindeer-sledge)
Possibility to enjoy the hotel saunas.
Thursday 29th January 2009
Morning breakfast
8:00 – 11:00 Session 5: Prospects of biomedical applications - II.
8:00-8:10 Session introduction – Christine Mummery (Leiden University, Nederland)
8:10-9:00 Cardiac differentiation – Christine Mummery (Leiden University, Nederland)
9:00-9:20 Coffee break
9:20-10:10 hESC derived cardiomyocytes in biomaterial scaffolds – Marisa Jaconi (Geneva University – Switzerland)
10:10-11:00 Differentiation of hES cells into liver cells – Petter Bjorquist (Goteborg, Sweden)
11:00 – 15:10
Outdoor activity: Safari – Snowmobile and Huskies sledges experience (2 groups who switch half way)
Includes a lunch in the wild.
15:10 – 19:00 Session 6: hESC and neural differentiation.
15:10-15:20 Session introduction – Oliver Brustle (Life&Brain, University of Bonn, Germany)
15:20-16:10 Stem Cell strategies for the Treatment of Parkinson’s disease – Ernest Arenas (Karolinska Institute, Stockholm, Sweden)
16:10-17:00 Neural differentiation – Oliver Brustle (Life&Brain, University of Bonn, Germany)
17:00-17:20 Coffee break
17:20-18:10 Differentiation of dopaminergic neurons – Elisabet Andersson (Karolinska Institute, Stockholm, Sweden)
18:10-19:00 Central and peripheral neurogenesis – Lorenz Studer (Sloan-Kettering institute, New York, USA)
Evening: Half board dinner in the hotel restaurant
Possibility to enjoy the hotel saunas.
Friday 30th January 2009
Morning breakfast
8:00 – 12:00 Session 7: Genetic & Epigenetic integrity.
8:00-8:10 Session introduction – Peter Andrews (Sheffield University, UK)
8:10-9:00 Genetic stability – Peter Andrews (Sheffield University, UK)
9:00-9:50 Epigenetics – Maria Berdasco (SNCR - Madrid, Spain)
9:50-10:20 Coffee break
10:20-11:10 Phenotypic heterogeneity – Peter Andrews (Sheffield University, UK)
11:10-11:40 Debriefing and conclusion words.
11:40 – 14:30 Lunch at the hotel
Outdoor activity OPTION 1 (from Wednesday): Free time
(wide range of activities not covered by ESTOOLS)
Outdoor activity OPTION 2 (from Wednesday): Snowshoes or cross-country ski (with guide/teacher for beginners)
12:15 or 18:00 Departure to Ivalo Airport. Transfer by bus from Saariselka
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